I agree with Michael: I don't think that multimedia is the best approach to learn bioinformatics skills. For one thing, there is not very much of it. Bioinformatics courses are a small fraction of all courses and institutions that post online lectures are a small fraction of all institutions. For another, it's not a time-efficient way to learn. An hour-long video requires your attention for an hour and is unlikely to teach you any practical skills. On the other hand, an online tutorial with code and examples allows you to dip in and out, skip sections, skim through and try out some practical approaches to problems, in your own time.
It's worth remembering that formal courses in bioinformatics are still a relatively "recent" phenomenon, only offered in the last 10 or even 5 years. Many working bioinformaticians are self-taught, biologists who turned to computer programming. I regard bioinformatics as quite difficult to teach formally because it is not really a field or a discipline; it is a collection of practical approaches for dealing with biological data, where "dealing with" means acquiring, storing, processing, analysing, interpreting and presenting. The best way to learn it is by doing it: grab yourself some data, learn some coding skills and see what you can do.
While I hate spamming, I would like to mention this online course on pharmaceutical biosciences at my former group as Uppsala University, which is free to attend (if you reached 150 ECTS). The content includes: databases drug, sequence, DNA, Statistical Experimental Design, cheminformatics, structure descriptors (molecular and protein sequence), sequence alignments, data analysis (statistics, chemometrics, proteochemometrics, rule based learning, QSAR), model validation, and lead identification and optimization.
The next course starts in January 2011, but you can already sign up here.