Question: Whole human genome sequence of COVID19 patient
0
gravatar for Tanvir Ahamed
7 weeks ago by
Sweden
Tanvir Ahamed 290 wrote:

I am looking for a whole human genome sequence of COVID19 patient. Is there anything published? Thanks in advance.

covid19 • 155 views
ADD COMMENTlink modified 7 weeks ago by swbarnes27.8k • written 7 weeks ago by Tanvir Ahamed 290
1

I am not aware of such a genome. Why do you think that would be useful?

ADD REPLYlink written 7 weeks ago by WouterDeCoster43k

Has been mooted that there may be 'protective' variants.

ADD REPLYlink written 7 weeks ago by bruce.moran790

Then you would want genome(s) of a person(s) who has recovered from or never got COVID in first place.

ADD REPLYlink written 7 weeks ago by genomax83k

Semantic argument, but let's not pretend that isn't of interest to bioinformaticians!

Protective means reducing an effect including mitigating entirely.

You'd want genomes, definitely plural, from a large cohort of patients, definitely that had tested positive for Covid-19, that had a well quantified phenotype of severity of disease.

I think it's a bit of reach, although colleagues are going to do this and I will be analysing it...

ADD REPLYlink written 7 weeks ago by bruce.moran790

Completely agree about your thought!!

ADD REPLYlink written 7 weeks ago by Tanvir Ahamed 290

Agree. A comparison of recovered patient and not- recovered (death) patient, could be an interesting point to study.

ADD REPLYlink written 7 weeks ago by Tanvir Ahamed 290

User "genomax" has one of the clear thought of application.

ADD REPLYlink written 7 weeks ago by Tanvir Ahamed 290

I am not sure if people are sequencing the genome of the affected/recovered patient or not. But hopefully, genome comparision will give us some interesting insight. Waiting for the public data !!

ADD REPLYlink written 7 weeks ago by Tanvir Ahamed 290

Don't count on it. It's not sufficiently relevant to justify spending thousands on sequencing these genomes while I can already tell you old age and comorbidities will get you killed.

ADD REPLYlink written 7 weeks ago by WouterDeCoster43k
0
gravatar for swbarnes2
7 weeks ago by
swbarnes27.8k
United States
swbarnes27.8k wrote:

That seems unlikely. What might be feasible is to find the genome of a cell culture line bring used in research.

ADD COMMENTlink written 7 weeks ago by swbarnes27.8k
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1291 users visited in the last hour