Question: Is There A Database That Can Be Used To Find The Drug Composition (Chemical Ingredients) Of A Given Drug?
2
gravatar for kewalyataruna
5.7 years ago by
kewalyataruna20 wrote:

Hi I would like to know how to find drug composition, means how to know all the chemicals which are ingredients of any particular drug like paracetamol etc. So please help me out by specifying any database which can help me out with my problem? Thanks

drug • 4.5k views
ADD COMMENTlink modified 2.6 years ago by Denise - Open Targets4.9k • written 5.7 years ago by kewalyataruna20

Do you just want active ingredients or do you want all of the binding and other agents that will vary per manufacturer?

ADD REPLYlink written 5.7 years ago by Devon Ryan89k
2
gravatar for quentin.delettre
5.7 years ago by
France
quentin.delettre430 wrote:

You can data mine the FDA, or the Dailymed : active ingredients and drug composition can be extracted. And for a subset of the FDA and European Medecine Agency active ingredients, you can check e-LEA3D

ADD COMMENTlink written 5.7 years ago by quentin.delettre430
2
gravatar for nidus
3.3 years ago by
nidus20
US/Atlanta
nidus20 wrote:

Sorry about reviving this, but it is a good question.

If you are looking for active ingredients, it is pretty straight forward to find them with RxNorm (alone or via UMLS).

As far as I know, if you are looking for inactive ingredients, this is more difficult.  As different manufacturers have different inactive ingredients, you will likely need to know the NDC (or equivalent) of the product you are wanting to know about.  From there, you could use UMLS to look up the FDA label ID (aka SPL Set ID) that corresponds to the NDC  (SAB=MTHSPL).  You can them obtain the XML for that label (either download the SPL library from the FDA web site, or possibly find a RESTful way to access it).  The XML file will have inactive ingredients listed with their Unique Ingredient Identifier codes.

If there is an easier way, please let me know.

JLA

ADD COMMENTlink written 3.3 years ago by nidus20
1
gravatar for Denise - Open Targets
2.6 years ago by
UK, Hinxton, EMBL-EBI
Denise - Open Targets4.9k wrote:

Have you tried ChEMBL?

ADD COMMENTlink written 2.6 years ago by Denise - Open Targets4.9k
0
gravatar for jokaxu
2.6 years ago by
jokaxu0
jokaxu0 wrote:

you can contact me for detail, we have the detail Drug database, mark.xu at mims.com

ADD COMMENTlink written 2.6 years ago by jokaxu0
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