Herald:The Biostar Herald for Wednesday, September 20, 2023
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The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here.

This edition of the Herald was brought to you by contribution from GenoMax, Istvan Albert, lethalfang, and was edited by Istvan Albert,

GitHub - poke1024/pyalign: Fast and Versatile Alignments for Python (github.com)

Fast and simple alignments in Python:

submitted by: Istvan Albert

Combined prediction and design reveals the target recognition mechanism of an intrinsically disordered protein interaction domain (www.pnas.org)

Alphafold AI in action. Two disordered proteins induce specific structures when they interact with each other.

submitted by: GenoMax

Leveraging the Latest Technologies for Cancer Mutation Detection (precision.fda.gov)

Blog post by an FDA lead scientist on precisionFDA on using the latest NGS technologies for cancer mutation detection.

submitted by: lethalfang

40 YouTube Channels Every Bioinformatician Should Follow - BIOINFORMATICAMENTE (bioinformaticamente.com)

Hi everyone. This is a very short post, actually it's a list of YouTube channels that you should follow if you are a bioinformatician or if it is your intention to pursue a career in bioinformatics.

submitted by: Istvan Albert

The specious art of single-cell genomics | PLOS Computational Biology (journals.plos.org)

We therefore examine the practical implications of low-dimensional embedding of single-cell data and find that extensive distortions and inconsistent practices make such embeddings counter-productive for exploratory, biological analyses. In lieu of this, we discuss alternative approaches for conducting targeted embedding and feature exploration to enable hypothesis-driven biological discovery.

submitted by: Istvan Albert

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