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1.9k
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Comment: C: Multiple testing correction issue
4.6 years ago by CY ▴ 730
0
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1
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1.9k
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Comment: C: Multiple testing correction issue
4.6 years ago by CY ▴ 730
0
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1
reply
1.1k
views
Tools that make mutation based phylogenetic tree figure
phylogenetic heterogeneity
4.6 years ago by CY ▴ 730
0
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0
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743
views
intuitive explaination of using HMM for alignment
HMM alignment
4.7 years ago by CY ▴ 730
1
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1
reply
1.1k
views
Capturing TCR from cfDNA
TCR cfDNA ctDNA
4.7 years ago by CY ▴ 730
0
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0
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1.5k
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TCR-Seq from bulk RNA-Seq data using TRUST
TCR-Seq RNA-Seq TRUST
4.7 years ago by CY ▴ 730
0
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0
replies
1.1k
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Does it make sense to use methylation data for GESA
GESA methylation expression
4.7 years ago by CY ▴ 730
0
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1
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1.5k
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Comment: C: Can we get absolute abundance of TCR using TCR-Seq?
4.8 years ago by CY ▴ 730
0
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1
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1.5k
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Comment: C: Can we get absolute abundance of TCR using TCR-Seq?
4.8 years ago by CY ▴ 730
0
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0
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727
views
Question regarding deFuse and fusion calling
RNA-Seq fusion deFuse
4.8 years ago by CY ▴ 730
0
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0
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1.0k
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Why can't solve tumor clonality using simple EM (Gaussian mixture) instead of MCMC(PyClone) or variational Bayes (SciClone)?
Clonality PyClone SciClone
4.9 years ago by CY ▴ 730
0
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0
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2.3k
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Comment: C: Is linearity maintained in linear regression of RNA-Seq?
4.9 years ago by CY ▴ 730
0
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1
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2.3k
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Comment: C: Is linearity maintained in linear regression of RNA-Seq?
4.9 years ago by CY ▴ 730
4
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5
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2.3k
views
Is linearity maintained in linear regression of RNA-Seq?
RNA-Seq
updated 4 months ago by 86k • written 4.9 years ago by ▴ 730
0
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1
reply
20k
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Comment: C: Deconvolution Methods on RNA-Seq Data (Mixed cell types)
4.9 years ago by CY ▴ 730
0
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0
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6.6k
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Comment: C: Log-transformed RNA-Seq data and linear regression
4.9 years ago by CY ▴ 730
0
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0
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6.6k
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Comment: C: Log-transformed RNA-Seq data and linear regression
4.9 years ago by CY ▴ 730
0
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0
replies
1.0k
views
Any method to solve RNA-Seq's non-linearity problem for deconvoluting immune cell?
RNA-Seq deconvolution
5.0 years ago by CY ▴ 730
3
votes
2
replies
1.9k
views
Somatic variant caller
next-gen variant calling somatic
updated 5.0 years ago by 20 • written 6.7 years ago by ▴ 730
3
votes
6
replies
880
views
Transcriptomic profile fluctuation between different time point
RNA-Seq
updated 5.0 years ago by 20 • written 5.1 years ago by ▴ 730
0
votes
2
replies
3.6k
views
Comment: C: Why use LASSO / elastic net in survival regression?
5.0 years ago by CY ▴ 730
2
votes
6
replies
3.6k
views
Why use LASSO / elastic net in survival regression?
survival analysis LASSO
updated 5.0 years ago by 26k • written 5.0 years ago by ▴ 730
0
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0
replies
1.1k
views
Any tools for co-mutation analysis just like WGCNA on co-expression analysis
Mutation Expression
5.0 years ago by CY ▴ 730
0
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0
replies
540
views
Forum: Have TCGA yielded expected research value yet?
TCGA
updated 6 months ago by 41k • written 5.0 years ago by ▴ 730
49
votes
9
replies
17k
views
7 follow
why PCA for RNA-Seq but tSNE for scRNA-seq?
pca RNA-Seq tSNE scRNA-seq
updated 5.0 years ago by ▴ 160 • written 5.5 years ago by ▴ 730
0
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1
reply
768
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Comment: C: Can remote, but same type, tissue be used as RNA-Seq normal control for tumor st
5.0 years ago by CY ▴ 730
0
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3
replies
768
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Can remote, but same type, tissue be used as RNA-Seq normal control for tumor study?
RNA-Seq
updated 5.0 years ago by ★ 4.0k • written 5.0 years ago by ▴ 730
0
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1
reply
4.0k
views
Comment: C: Why NMF for mutation signature analysis
5.0 years ago by CY ▴ 730
13
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8
replies
4.0k
views
Why NMF for mutation signature analysis
mutation NMF signature
5.0 years ago by CY ▴ 730
0
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1
reply
4.0k
views
Comment: C: Why NMF for mutation signature analysis
5.0 years ago by CY ▴ 730
0
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0
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4.0k
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Comment: C: Why NMF for mutation signature analysis
5.0 years ago by CY ▴ 730
0
votes
0
replies
880
views
Comment: C: Transcriptomic profile fluctuation between different time point
5.1 years ago by CY ▴ 730
1
vote
0
replies
880
views
Comment: C: Transcriptomic profile fluctuation between different time point
5.1 years ago by CY ▴ 730
0
votes
1
reply
880
views
Comment: C: Transcriptomic profile fluctuation between different time point
5.1 years ago by CY ▴ 730
1
vote
4
replies
3.6k
views
Any tools for predicting binding affinity between TCR and epitode?
prediction TCR cancer
updated 5 months ago by 41k • written 5.5 years ago by ▴ 730
0
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1
reply
988
views
Comment: C: Gene expression distribution (non-DE and DE)
5.1 years ago by CY ▴ 730
0
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1
reply
988
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Comment: C: Gene expression distribution (non-DE and DE)
5.1 years ago by CY ▴ 730
2
votes
5
replies
988
views
Gene expression distribution (non-DE and DE)
RNA-Seq differential expression
updated 5.1 years ago by 86k • written 5.1 years ago by ▴ 730
1
vote
0
replies
4.1k
views
Shannon index vs Simpson index in evaluating TCR diversity
TCR-Seq TCR diversity
5.1 years ago by CY ▴ 730
0
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0
replies
4.1k
views
Answer: A: Correcting for tumor purity in tumor evolution analysis
5.1 years ago by CY ▴ 730
0
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1
reply
1.3k
views
Comment: C: Low VAF (around 7%) mutated gene prevalent in cancer patient (3/4), driver?
5.1 years ago by CY ▴ 730
0
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1
reply
1.3k
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Comment: C: Low VAF (around 7%) mutated gene prevalent in cancer patient (3/4), driver?
5.1 years ago by CY ▴ 730
3
votes
5
replies
1.3k
views
Low VAF (around 7%) mutated gene prevalent in cancer patient (3/4), driver?
mutation VAF driver gene
5.1 years ago by CY ▴ 730
0
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0
replies
6.2k
views
Comment: C: What kind of distribution to you expect to see for RNA-Seq expression levels?
5.1 years ago by CY ▴ 730
0
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0
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1.3k
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Comment: C: Would different enrichment tools result differently by defining pathway differen
5.1 years ago by CY ▴ 730
4
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4
replies
1.3k
views
Would different enrichment tools result differently by defining pathway differently
RNA-Seq enrichment analysis
5.2 years ago by CY ▴ 730
0
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1
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1.3k
views
Comment: C: Difference between gene set enrichment and pathway enrichment
5.2 years ago by CY ▴ 730
2
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3
replies
1.6k
views
Any tools to estimate the relative abundance of immune cell in tumor
RNA-Seq immune fraction absolute estimate
updated 5.2 years ago by 86k • written 5.2 years ago by ▴ 730
0
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0
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1.6k
views
Comment: C: Any tools to estimate the relative abundance of immune cell in tumor
5.2 years ago by CY ▴ 730
1
vote
0
replies
879
views
Can any tool distinguishs immune inflammation / immune excluded phenotype?
RNA-Seq TCR-Seq ESTIMATE
5.2 years ago by CY ▴ 730
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