Question: Cell Type Marker Databases?
gravatar for Adam Cornwell
7.9 years ago by
Adam Cornwell420
United States
Adam Cornwell420 wrote:

Hi, I've been looking to see if there is any kind of public database or resource for cell type-specific markers. These would include genes for proteins that can uniquely identify a cell population using techniques such as FACS. I've tried a variety of different search terms, but haven't managed to come up with much. I figured I would check here to make sure I may not be missing something out there before resorting to literature mining and meta-analysis of GEO data. So far the best I have found are lists of sequences used in commercial cell type validation PCR arrays, for which no citations are given...

Thank you

database • 10k views
ADD COMMENTlink modified 18 months ago by of20 • written 7.9 years ago by Adam Cornwell420
gravatar for of
18 months ago by
of20 wrote:

Here is one such marker database:

ADD COMMENTlink written 18 months ago by of20
gravatar for Malachi Griffith
7.9 years ago by
Washington University School of Medicine, St. Louis, USA
Malachi Griffith18k wrote:

For immune (and other) cell types you could start with some resources related to human clusters of differentiation, used in Immunophenotyping. Wikipedia has a decent list of CD molecules. This CD Antigens Table is a fairly rich resource.

There are also specific projects that seek to characterize the distinguishing genes of each tissue. For example the Human Protein Atlas, and the Mouse Atlas of Gene Expression.

ADD COMMENTlink written 7.9 years ago by Malachi Griffith18k
gravatar for Khader Shameer
7.9 years ago by
Manhattan, NY
Khader Shameer18k wrote:

If you are looking at humans, I would consult Human Proteinpedia (See this page for data categorized using annotations and experimental platforms) and Human Protein Atlas before starting a de-novo literature curation or meta-analysis.

ADD COMMENTlink written 7.9 years ago by Khader Shameer18k
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