List Of All Transcription Factors In Human
Is there any list of all transcription factors in humans and their respective ensemble gene id?
I have been trying to find one but haven't been able to do so. In this paper
they mention that there are around 2,600 proteins that function as TFs but they do not provide a table or a list as supplementary.
I am curious to know if someone has run into such table.
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Perhaps a better starting point than GO accessions would be a TF database. A couple of examples (easily found via web search for "transcription factor" + database):
AnimalTFDB - 1544 entries for H.sapiens
DBD - 2886 (predicted) entries for H.sapiens
downloads and identifiers such as Ensembl gene ID, which are easily converted to Entrez gene ID using BioMart or similar.
Try the UniProt interface e.g.
1,799 results for "transcription factor"AND reviewed:yes AND organism:"Homo sapiens (Human) "in UniProtKB
These are name matches so its not completely clean as you get some co-factors. You could pick out the InterPro domains and or look at the GO terms that fit and make a union
You can then use the "Customise results" to get the Ensembl ID or any other X-ref
10.7 years ago by
Don't overlook the utility of the list of TFs used by the FANTOM consortium. See the suppl file for the paper by Ravasi
et al (2010) Cell 140:744-752.
TRANSFAC and JASPAR CORE are curated TF databases, which include human transcription factors. The second database is free and aims at non-redundancy, while the first is not free and is redundant. Both databases can include accession information for recovering protein names from external sites.
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http://www.tfcheckpoint.org/ manually curated list of mammalian transcription factors, including specific dbTFs