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Wright'S Fst And Weir & Cockerham'S Fst Estimator - Simple Explanation Of The Difference
Wright'S Fst And Weir & Cockerham'S Fst Estimator - Simple Explanation Of The Difference
Comment: Polygenic Risk Score calculation
A: De-duplicate UMI at FASTQ level
Answer: Getting the protein Domain architecture from a domtblout
Answer: Getting the protein Domain architecture from a domtblout
Multiple testing correction in RNA-Seq
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Comment: Polygenic Risk Score calculation
by
ashaneev07
▴ 20
Then how it will be supporting risk snps in individual patient sample? and so it is like a population based study. could you please make a…
Comment: Salmon ~ Effective Length
by
GenoMax
142k
> assuming its impossible to calculate insert size when paired end reads do not overlap in an RNA library If you have a reference availabl…
Comment: How to build ribosomal interval files to use in CollectRnaSeqMetrics for hg38.p
by
naaj
• 0
How to make sure the larger rRNAs are included?
Comment: Error with pheatmap - 'from' must be a finite number
by
SamGG
▴ 20
Please report ``` all(is.finite(mat.z)) all(is.finite(dist(mat.z))) pheatmap(mat.z, cluster_rows = FALSE, cluster_cols = FALSE) pheatmap(ma…
Comment: finding highly divergent orthologs using exonerate
by
dthorbur
★ 2.0k
It might be worth trying to cluster sequences with a few intermediate species too. Then the centroid of the cluster can theoretically be on…
Comment: Error with pheatmap - 'from' must be a finite number
by
vmpsb
• 0
> any(is.infinite(mat.z)) [1] FALSE
Comment: Error with pheatmap - 'from' must be a finite number
by
vmpsb
• 0
Thanks, how should I proceed?
Comment: Z score
by
ATpoint
82k
Difference is that plotting Z-scores plots each group and logFC plots differences between groups. Simply a different way of showing things.…
Comment: Is there any minimum number of counts in scRNAseq to consider that a gene is exp
by
ATpoint
82k
> I am asking this particular question due that I am used to work with bulk RNAseq data and I usually consider a gene is worth to focus in …
Comment: How to decrease the motif score?
by
dthorbur
★ 2.0k
You seem to indicate you found motifs. So why do you now want to reduce the score? Do you want to narrow your search to fewer motifs to mov…
Comment: coding and non-coding region of the viral genome
by
dthorbur
★ 2.0k
Are there already annotations published for the genome? If so, I doubt there is a dedicated tool since this is a simple task of parsing the…
Answer: Error with Pheatmap ()
by
zx8754
11k
Errors and warnings are clear, we can reproduce them with this simple example Somewhere *pheatmap* is getting a minimum value excluding NA…
Comment: Polygenic Risk Score calculation
by
zx8754
11k
A single PRS number is meaningless without background data like 1000 genomes, UK Biobank, etc.
Comment: Salmon vs Kallisto vs RSEM
by
Mohamed Abderrahmane
▴ 20
Thank you so much for your response. The two links are really helpful. I appreciate it. Have a nice day!
Comment: vg autoindex seems stuck after a week of running
by
StevieP
▴ 10
Thanks for this. As a follow-up, the process did indeed complete after 8.5 days so I guess my concerns were unwarranted in the end.
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