If I may preface this with a little observation, I've noticed that when one bioinformatic community talks about another, the Biostars folk are consistently respectful and positive in the face of sometimes quite harsh criticism. Perhaps one needs an easy-going mindset to read/answer 10 boring questions before they come across 1 that makes them stop and think. Regardless, I hope that continues :)
So it appears that for all the reasons predicted on the other thread, the Bioinformatics SE isn't picking up the sort of steam that is perhaps desired: https://bioinformatics.meta.stackexchange.com/questions/40/is-there-a-large-enough-community-to-sustain-this-site
Now I think actually this is a bit of a shame, because any amount of effort spent making bioinformatics more of a community thing is effort well spent. A lot of the headaches in bioinformatics are dealing with decisions isolated people made, be it a weird analysis, non-intuitive tooling, data formats that don't store what other people want, etc. Less isolation is always a good thing.
But as it appears that isn't going to go through, perhaps now would be a good time for us to listen to the fair criticism that was received about Biostars and, essentially, make a prioritised list of ways Biostars could be better. Perhaps this whole SE affair will have a happy ending, if it promotes changes in the Biostars network that ultimately grows the community.
The biggest criticism I've heard of Biostars so far is the low quality questions/answers. Personally, I don't see low quality answers (which probably means I'm the one providing them...!), but I do see low-quality questions. Of course. When most people get started in the field because data.fastq was e-mailed to them by a collaborator, this is not unexpected. Perhaps the solution is to have an "advanced question" type, so one can filter on only the advanced questions (that need a certain amount of rep to ask)? I don't know. All I'm saying is, now would be a good time to think about how Biostars can fill the void that is clearly there if people want a SE so much. The end-goal would be to go to SE after the decision to close has been made, with a "we heard you and we changed - try us out now."
Otherwise... I'm worried that there will be some resentment to Biostars. I'm already starting to see it actually. The typical "our community would be much better if only yours didn't exist!" stuff. Downvote logic.