Hi Heididunst, my few points
It about more than 5 months for COVID-19 pandemic but still we far from developing any vaccine
If we look at time needed for vaccine development (for previous diseases), one might understand it's not possible to get something reasonable in the span of 1 year, let alone 5 months
However, to date numerous researcher have developed n number of bioinformatics tools, techniques and models claiming these tools will help in early detection and prevention of any disease outbreak.
IMO, the ultimate goal of any bionformatics tool is not early prediction/prevention. It only helps you on your way, with other tools and knowledge to reach a potential solution (in this case prediction). BTW, could you may be give an example which tool claimed it will detection and prevent a disease outbreak? Curious to see.
It very strange that in this time of pandemic nothing seems working well. My question is then what is the use of these techniques when we are failing to do so. Or these tools are just for mere publication and promotion
I agree nothing seems to be working well, that's because we were not familiar with what virus is doing inside a human body. I don't see a tool working very well in normal case failed all of a sudden in case of a pandemic. Also, the field of bioinformatics is not only to help in situations like pandemics, but there are 1000s of diseases humans are dealing with. I am sure bioinformatics/tools played a good role here and there. Don't you think so?
Re single cell techniques
Don't you think single-cell techs are well established? They are producing very valuable insights for other diseases e.g. cancers, alzheimer's disease etc. IMO, using single-cell techs will give far more insights than 'established techniques', for example, any specific cell population that changed their transcriptome after infection, what important genes we can identify to potentially target?
The current funding agencies already underestimates the value of bioinformatics/software tools in advancing biology. IMO, wet-lab & dry-lab are equally important. However, I wouldn't call wet-lab as real and bioinformatics otherwise, both are real and sciences.
But as a bioinformatician, I feel we bioinformatician have failed. There is no point in giving bioinformatics as a special status
If yet all, I would blame govt for not taking enough measures in handling situations like this. Many a times, experts advised govt what to do to prevent pandemics based on previous experiences, nevertheless, they have done nothing (can't remember the source of a simulation study performed in a US state in 1950s or in that time).
There are many points, than stated, we should consider before we say 'Rest in peace to all bioinformatics tools and techniques'