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2
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7
replies
1.3k
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Why can we still be able to continuously discover new cancer driver bioinformatically these days?
driver gene cancer
4.6 years ago by CY ▴ 750
2
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0
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1.3k
views
Comment: C: Arm-level SCNA does not change mRNA expression level?
4.6 years ago by CY ▴ 750
1
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1
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1.3k
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Comment: C: Arm-level SCNA does not change mRNA expression level?
4.6 years ago by CY ▴ 750
0
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1
reply
1.3k
views
Comment: C: Why can we still be able to continuously discover new cancer driver bioinformati
4.6 years ago by CY ▴ 750
0
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1
reply
1.3k
views
Comment: C: Why can we still be able to continously discover new cancer driver bioinformatic
4.6 years ago by CY ▴ 750
0
votes
1
reply
1.3k
views
Comment: C: Why can we still be able to continously discover new cancer driver bioinformatic
4.6 years ago by CY ▴ 750
0
votes
1
reply
2.8k
views
Answer: A: Whole Blood Samples of Cancer Patients from TCGA?
updated 4.6 years ago by 44k • written 8.7 years ago by ▴ 750
0
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0
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11k
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Comment: C: how to use ESTIMATE to infer tumor purity and stromal score from RNA-seq data?
4.6 years ago by CY ▴ 750
1
vote
5
replies
1.1k
views
Composition of low mappable region in human genome
mappability repetitive region homologous region
updated 4.7 years ago by 20 • written 4.7 years ago by ▴ 750
0
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0
replies
642
views
Any absolute quantification method for detection of polyploidy tumor sample
PCR RNA-Seq
4.7 years ago by CY ▴ 750
0
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0
replies
8.5k
views
Comment: C: What is the best way to combine machine learning algorithms for feature selectio
4.7 years ago by CY ▴ 750
0
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1
reply
1.1k
views
Comment: C: Composition of low mappable region in human genome
4.7 years ago by CY ▴ 750
0
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1
reply
1.1k
views
Comment: C: Composition of low mappable region in human genome
4.7 years ago by CY ▴ 750
0
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0
replies
2.7k
views
Comment: C: Regions to exclude in CNV analysis
4.7 years ago by CY ▴ 750
1
vote
2
replies
1.2k
views
How splice-aware aligner (RNA-Seq) deal with long gap (intron) penalty
RNA-Seq STAR alignment hisat tophat
updated 4.7 years ago by 20 • written 4.7 years ago by ▴ 750
0
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0
replies
907
views
Comment: C: How does base quality / mapping quality affect germline calling
4.7 years ago by CY ▴ 750
1
vote
3
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907
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How does base quality / mapping quality affect germline calling
haplotypecaller germline calling MAPQ
4.7 years ago by CY ▴ 750
0
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1
reply
3.3k
views
Comment: C: Infer somatic mutations without normal control
4.7 years ago by CY ▴ 750
0
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0
replies
1.3k
views
Comment: C: non-reference allele didn't be called into vcf by HC
4.7 years ago by CY ▴ 750
0
votes
0
replies
5.6k
views
Comment: C: "Protein search using Blastp" vs "protein search using hmm profile"
4.7 years ago by CY ▴ 750
0
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1
reply
1.3k
views
Comment: C: non-reference allele didn't be called into vcf by HC
4.7 years ago by CY ▴ 750
0
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4
replies
1.3k
views
non-reference allele didn't be called into vcf by HC
haplotypecaller vcf
updated 4.7 years ago by 88k • written 4.7 years ago by ▴ 750
0
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2
replies
3.3k
views
Comment: C: Infer somatic mutations without normal control
4.7 years ago by CY ▴ 750
0
votes
1
reply
940
views
Dispersion shrinkage in DESeq2: LOESS instead of negative binomial based GLM?
RNA-SEQ DESeq
4.8 years ago by CY ▴ 750
1
vote
5
replies
994
views
Archieve of homologous nucleotide sequence across genome
sequence
updated 4.8 years ago by ▴ 130 • written 4.8 years ago by ▴ 750
0
votes
1
reply
994
views
Comment: C: Archieve of homologous nucleotide sequence across genome
4.8 years ago by CY ▴ 750
0
votes
0
replies
995
views
XHMM calls CNV on a number of normal samples
CNV XHH
4.8 years ago by CY ▴ 750
0
votes
0
replies
1.7k
views
Comment: C: Library size normalization during CNV calling from genomically doubled tumor tis
4.8 years ago by CY ▴ 750
0
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9
replies
1.7k
views
Library size normalization during CNV calling from genomically doubled tumor tissue
CNV
updated 4.8 years ago by ▴ 550 • written 4.9 years ago by ▴ 750
0
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1
reply
1.7k
views
Comment: C: Library size normalization during CNV calling from genomically doubled tumor tis
4.8 years ago by CY ▴ 750
1
vote
0
replies
1.3k
views
Comment: C: Noisy CNV background in old FFPE sample
4.9 years ago by CY ▴ 750
1
vote
1
reply
1.3k
views
Comment: C: Noisy CNV background in old FFPE sample
4.9 years ago by CY ▴ 750
6
votes
5
replies
1.3k
views
Noisy CNV background in old FFPE sample
CNV FFPE
updated 4.9 years ago by ★ 2.8k • written 4.9 years ago by ▴ 750
0
votes
0
replies
998
views
Comment: C: Effect size in power analysis when dealing with Poisson based variant caller
4.9 years ago by CY ▴ 750
1
vote
3
replies
998
views
Effect size in power analysis when dealing with Poisson based variant caller
variant calling
updated 4.9 years ago by ▴ 550 • written 4.9 years ago by ▴ 750
0
votes
0
replies
1.1k
views
Difference between mpileup and HaplotypeCaller -ERC BP_RESOLUTION
variant calling haplotypecaller mpileup
4.9 years ago by CY ▴ 750
3
votes
7
replies
1.5k
views
Why methylation sequencing requires much less sequencing depth than DNA-Seq?
methylation WGBS
updated 5.0 years ago by 8.2k • written 5.0 years ago by ▴ 750
0
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1
reply
1.5k
views
Comment: C: Why methylation sequencing requires much less sequencing depth than DNA-Seq?
5.0 years ago by CY ▴ 750
0
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1
reply
1.5k
views
Comment: C: Why methylation sequencing requires much less sequencing depth than DNA-Seq?
5.0 years ago by CY ▴ 750
0
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1
reply
1.6k
views
Comment: C: Why do so many biomarker based classifiers claim high accuracy but rarely used i
5.0 years ago by CY ▴ 750
21
votes
4
replies
1.6k
views
Why do so many biomarker based classifiers claim high accuracy but rarely used in clinical setting?
biomarker
5.0 years ago by CY ▴ 750
0
votes
1
reply
991
views
Mutated gene based pathway enrichment
enrichment mutation
updated 5.0 years ago by ▴ 990 • written 5.0 years ago by ▴ 750
0
votes
0
replies
809
views
Why seed and fuzzy-search in MIGEC?
MIGEC MUI tcr
5.1 years ago by CY ▴ 750
0
votes
0
replies
9.8k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
5.1 years ago by CY ▴ 750
0
votes
0
replies
9.8k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
5.1 years ago by CY ▴ 750
0
votes
2
replies
9.8k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
5.2 years ago by CY ▴ 750
0
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1
reply
9.8k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
5.2 years ago by CY ▴ 750
0
votes
1
reply
9.8k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
5.2 years ago by CY ▴ 750
0
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0
replies
9.8k
views
Comment: C: Why can't use t-test for differential expression (negative binomial distribution
5.2 years ago by CY ▴ 750
27
votes
17
replies
9.8k
views
Why can't use t-test for differential expression (negative binomial distribution assumed)
RNA-Seq
updated 5.2 years ago by 14k • written 5.2 years ago by ▴ 750
278 results • Page 2 of 6
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