First I would ask you how did you (or someone else) call the variants? Which file format(s) do you have? Is that VCF or tool-specific output? Do you have normal and diseased samples? Which questions are you asking? Are you looking for GUI or command line tools?
For a comprehensive output, that returns a MAF format that you can use in IGV (link in comment above), you can use oncotator from Broad. for a command line tool you can use annovar and, as mentioned above, SnpEff.