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Recent Replies
Comment: NGS forensics: how to know if data is fabricated
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IMO (and unfortunately) there needs to be an effort to develop these algorithms.
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the samples that are `./.` have no coverage (or not enough to call a genotype) and the `0/0` are homozygous reference
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Did you download the complete dataset available from ENA/NCBI SRA? This is an older dataset (from 2012) with a total of 1146212 reads and 1…
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Hello, I want to know that why my gVCF files have "./." besides "0/0", "1/1"?
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Comment: gvcf joint calling
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![enter image description here][1]
[1]: /media/images/15eedc1a-b2c6-4966-be39-b5173dab
And I confused with the file that has "./." and…
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![enter image description here][1]
[1]: /media/images/16fd502c-4e01-4f56-8562-0e0d4aac
Okay, this is the merged gVCF file.
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Enzymes under the umbrella of `1.1.1.-` work `with NAD(+) or NADP(+) as acceptor`. That only tells you about their cofactors, but not about…
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I don't think people have undertaken the effort to create an anomaly detector for RNAseq -- people's efforts are dedicated towards developi…
Comment: NGS forensics: how to know if data is fabricated
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dsull
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I'd say post on pubpeer -- it's the best forum for this sort of discussion.
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> This is a super-interesting question from an algorithmic standpoint
Ya, I was hoping to find some algorithm that would compare say a 're…
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Thank you for your valuable suggestion!
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> My first question would be how strong your background in such analysis
> is.
Very strong. PhD+several years working in the field.
> Wot…
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My first question would be how strong your background in such analysis is. Claim of fabrication is very serious, so be 100% sure to back it…
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This is a super-interesting question from an algorithmic standpoint (devising a model that can distinguish real from synthetic reads) but I…
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