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1,000 results • Page
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6
votes
7
replies
1.1k
views
Forum:
Generic avatars, not gravatars?
technical
avatar
2.1 years ago by
Michael
54k
5
votes
0
replies
2.9k
views
Forum:
Correct method of Merging/Integrating multiple single cell dataset using Seurat
seurat
scrnaseq
2.2 years ago by
rohitsatyam102
▴ 870
0
votes
0
replies
548
views
Forum:
Phylogenomics in the presence of gene flow
hybridisation
introgression
gene-flow
Phylogenomics
2.2 years ago by
jeronimocid93
• 0
2
votes
2
replies
1.0k
views
Forum:
Bioinformatician Jobs: Remote Flexible is possible?
remote-jobs
bioinformatician
updated 23 months ago by
Ram
44k • written 2.2 years ago by
Marcela
▴ 20
15
votes
11
replies
4.8k
views
9 follow
Forum:
Methodological problems are extremely common for enrichment analysis - beware the pitfalls before you publish
GSEA
DAVID
enrichment-analysis
-geneontology
updated 12 months ago by
Ram
44k • written 2.2 years ago by
mark.ziemann
★ 1.9k
0
votes
0
replies
485
views
Forum:
CIRCexplorer2 - Getting Count Matrix
CIRCexplorer2
counts
circRNA
2.2 years ago by
akamonto
• 0
3
votes
5
replies
1.1k
views
Forum:
1000 genomes data?
DNA
1000genomes
variation
updated 2.2 years ago by
Ram
44k • written 2.2 years ago by
datanerd
▴ 520
0
votes
0
replies
533
views
Forum:
What kind of analysis automation or pipeline is most needed in genomic data analysis right now?
dna
genome
analysis
programming
statistics
updated 2.2 years ago by
ATpoint
82k • written 2.2 years ago by
d
• 0
29
votes
10
replies
6.5k
views
10 follow
Forum:
Interesting/useful/beautiful bio sequence viz tools
viz
python
visualisation
updated 14 months ago by
Ram
44k • written 6.2 years ago by
Joe
21k
3
votes
6
replies
2.2k
views
Forum:
A Css For Small Screen Devices?
meta
updated 15 months ago by
Ram
44k • written 12.1 years ago by
14134125465346445
★ 3.6k
12
votes
6
replies
3.0k
views
Forum:
M.S. Bioinformatics and Computational Biology: Will I be able to find a job after graduation? I'm worried...
career
Masters
Graduation
updated 23 months ago by
Ram
44k • written 2.2 years ago by
CMPanda
▴ 20
0
votes
3
replies
939
views
Forum:
Project Topics on bioinformatic
Data-analysis
Coding
Molecular-biology
updated 12 months ago by
Ram
44k • written 2.2 years ago by
Abdullahi
• 0
0
votes
4
replies
1.3k
views
Forum:
Declining multithreading Diamond performance on decent dual AMD Epyc 7643 server
diamond
performance
EPYC
7643
multithreading
AMD
poor
updated 2.2 years ago by
GenoMax
142k • written 2.2 years ago by
Balazs Horvath
▴ 10
3
votes
1
reply
942
views
Forum:
How to download multiple .gz files from Ensembl Protists database
wget
protist
ensembl
updated 3 months ago by
BioinfGuru
★ 1.7k • written 2.2 years ago by
rohitsatyam102
▴ 870
3
votes
4
replies
2.6k
views
Forum:
Bioinformatics Research Topics/Areas that Everyone should take a look / Current Trends
research-area
postgraduates
updated 15 months ago by
Ram
44k • written 2.3 years ago by
pfee418
▴ 10
1
vote
0
replies
563
views
Forum:
Continue exploring Bioinformatics and improving Bioinformatics Skills
postgraduate
bioinformatics-skills
updated 15 months ago by
Ram
44k • written 2.3 years ago by
pfee418
▴ 10
0
votes
1
reply
783
views
Forum:
ensemble VEP server is down
VEP
ensemble
updated 2.3 years ago by
ATpoint
82k • written 2.3 years ago by
Jiji
• 0
15
votes
10
replies
2.0k
views
7 follow
Forum:
Tips and tricks to improve data visualization in bioinformatics
visualization
ggplot2
plot
updated 2.3 years ago by
Mensur Dlakic
★ 27k • written 2.3 years ago by
Papyrus
★ 2.9k
3
votes
8
replies
1.6k
views
Forum:
What are the pain points of using Genomics on the cloud today?
datasharing
pipelines
workspaces
cloud
genomics
updated 2.3 years ago by
Jeremy Leipzig
22k • written 2.3 years ago by
datanerd
▴ 520
0
votes
0
replies
564
views
Forum:
UniProt survey about programmatic access
documentation
api
survey
uniprot
updated 2.3 years ago by
Pierre Lindenbaum
162k • written 2.3 years ago by
Elisabeth Gasteiger
★ 2.4k
4
votes
9
replies
3.1k
views
Forum:
100% variance explained on one PC in DESeq2 PCA?
RNA-Seq
DESeq2
2.3 years ago by
melatoninixo
▴ 10
17
votes
14
replies
3.4k
views
Forum:
Asking for feedback on a Python library for computing alignments
alignment
Python
updated 11 months ago by
Alexander
▴ 220 • written 2.4 years ago by
bernhard.liebl
▴ 60
0
votes
1
reply
652
views
Forum:
Statistical methods Books Recommendation
Books
Recommendation
updated 2.3 years ago by
ATpoint
82k • written 2.3 years ago by
GK1610
▴ 110
0
votes
0
replies
481
views
Forum:
Is there any limitation for number of samples in AUC analysis ?
curves
ROC
2.3 years ago by
sabaghianamir70
▴ 70
6
votes
5
replies
4.0k
views
6 follow
Forum:
How is the job outlook in 2020 ?
career
outlook
updated 23 months ago by
Ram
44k • written 5.9 years ago by
plus.zer090
• 0
6
votes
5
replies
1.2k
views
6 follow
Forum:
Usability of depiction of individual reads in genome browser visualization
visualization
browser
genome
updated 2.4 years ago by
Istvan Albert
100k • written 2.4 years ago by
massa.kassa.sc3na
▴ 600
4
votes
7
replies
1.8k
views
Forum:
Data Base management system for data lake: Cassandra vs MongoDB vs Apache HBase
HBase
Cassandra
MongoDB
Data-Lake
updated 2.4 years ago by
Carambakaracho
★ 3.2k • written 2.4 years ago by
ResearchR
▴ 120
9
votes
8
replies
5.2k
views
9 follow
Forum:
insert figure and code in the post of Biostars?
meta
biostars
updated 14 months ago by
Ram
44k • written 9.0 years ago by
Zhilong Jia
★ 2.2k
7
votes
2
replies
1.6k
views
Forum:
What are the most influential Bioinformatics/Computational Biology papers/methods/discoveries of 2021?
snp
papers
survey
updated 15 months ago by
Ram
44k • written 2.4 years ago by
Raony Guimarães
★ 1.4k
0
votes
1
reply
784
views
Forum:
What are the most important papers/methods in Genomics/Bioinformatics of 2021?
publications
updated 11 months ago by
Ram
44k • written 2.4 years ago by
carlopecoraro2
★ 2.5k
24
votes
11
replies
4.3k
views
7 follow
Forum:
In 2022 is Perl and Ruby programming languages still useful for bioinformatics?
ruby
perl
updated 2.4 years ago by
Juke34
8.6k • written 2.4 years ago by
narendra75
• 0
0
votes
4
replies
877
views
Forum:
Terms (like atlas, map, and archive) on database description
database
2.4 years ago by
bioinformaticsBoy
▴ 10
2
votes
2
replies
812
views
Forum:
How much are companies willing to pay for microbiome data?
NGS
metagenomics
microbiome
2.4 years ago by
maa4618
• 0
19
votes
1
reply
4.5k
views
Forum:
Best programming language for bioinformatics - R Language
programming
R
updated 14 months ago by
ATpoint
82k • written 3.3 years ago by
Novogene
▴ 420
6
votes
7
replies
1.4k
views
Forum:
How to change my email address
meta
biostars
updated 2.5 years ago by
XiBon
• 0 • written 3.2 years ago by
Bosberg
▴ 50
9
votes
11
replies
3.4k
views
6 follow
Forum:
2021: state and usage of compressed file standards better than BAM and FASTQ
bam
compression
fastq
updated 22 months ago by
quentin54520
▴ 120 • written 3.1 years ago by
William
★ 5.3k
10
votes
3
replies
4.8k
views
Forum:
Trimming tools - your experience please?
trimming
updated 2.5 years ago by
i.sudbery
19k • written 2.5 years ago by
paigemiller
▴ 20
8
votes
9
replies
1.8k
views
Forum:
Most useful public genomic/genetic databases/tools/applications
public-data
genomics
Genetics
open-access
updated 15 months ago by
Ram
44k • written 2.5 years ago by
datanerd
▴ 520
74
votes
14
replies
30k
views
12 follow
Forum:
Bioinformatics Consulting Thoughts
consulting
updated 23 months ago by
Ram
44k • written 14.0 years ago by
Will
4.5k
6
votes
3
replies
1.2k
views
Forum:
Computational Biology Conference
biology
computational
science
research
conference
updated 2.5 years ago by
WouterDeCoster
47k • written 2.5 years ago by
Marco Pannone
▴ 790
0
votes
1
reply
746
views
Forum:
UK supercomputer Cambridge-1 vs SDSC vs TACC
SDSC
TACC
HPC
Cambridge-1
updated 2.5 years ago by
GenoMax
142k • written 2.5 years ago by
Shicheng Guo
★ 9.4k
0
votes
1
reply
733
views
Forum:
Official/centralized/designated genetic/biological knowledge graph?
knowledge
graph
updated 2.5 years ago by
Carlo Yague
8.7k • written 2.5 years ago by
Victor
• 0
0
votes
0
replies
548
views
Forum:
Targeted sequencing and phylogenetics
SC
sequencing
exome
gene_panel
updated 15 months ago by
Ram
44k • written 2.5 years ago by
Bioda
• 0
2
votes
7
replies
3.1k
views
Forum:
M1 Pro/Max and future
Max
M1
M2
Pro
Mac
updated 2.5 years ago by
GenoMax
142k • written 2.6 years ago by
fredhstein
▴ 20
21
votes
8
replies
7.6k
views
Forum:
Is there ever a good reason to use a log transformation instead of Box-Cox?
data
skew
transformation
power
updated 2.6 years ago by
Istvan Albert
100k • written 2.6 years ago by
Mensur Dlakic
★ 27k
6
votes
2
replies
802
views
Forum:
Biology undergraduate looking for mentor
computational-biology
Biology
mentor
Toronto
updated 2.6 years ago by
Ram
44k • written 2.6 years ago by
Blcksrvl
• 0
1
vote
7
replies
1.4k
views
Forum:
Does it matter where I get my PhD? I am currently a masters student.
advice
PhD
Masters
2.6 years ago by
nickroseae
▴ 10
16
votes
7
replies
2.0k
views
Forum:
Will a user #100000 get Tesla Model 3?
milestone
updated 2.6 years ago by
Istvan Albert
100k • written 2.6 years ago by
Mensur Dlakic
★ 27k
2
votes
8
replies
1.9k
views
Forum:
Non biology & computer professional interested in bioinformatics
computer-science
machine-learning
updated 15 months ago by
Ram
44k • written 2.6 years ago by
ASU
• 0
0
votes
0
replies
651
views
Forum:
PhD Bioinformatics Remote positions
PhD
updated 23 months ago by
Ram
44k • written 2.6 years ago by
fernandogs97
▴ 30
1,000 results • Page
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Recent Votes
A: Fold change - a final explanation
Comment: scRNA-seq quality control
Comment: How to get the ratio of allele counts from GATK derived VCF file?
Setting up Aspera Connect (ascp) on Linux and macOS
Setting up Aspera Connect (ascp) on Linux and macOS
Answer: Genes' fpkm values through cufflink
Answer: Genes' fpkm values through cufflink
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Recent Replies
Comment: Z score
by
Akash D
▴ 40
Alright! Got you...
Comment: Ideal PC configurations and operating system for bioinformatics laboratory
by
i.sudbery
19k
It very much depends on whether the OP does want/need to do the CellRanger runs locally or not. Doesn't really matter if its only occasion…
Comment: log2 fold change in RNA-seq analysis
by
Mensur Dlakic
★ 27k
Everything is already explained on this page, just read everything already written above. Specifically, [**this comment**][1]. [1]: htt…
Answer: log2 fold change in RNA-seq analysis
by
May Ling
• 0
Good day everyone, Sorry I found a bit confusing and would appreciate if I could clarify on the calculation. I am using DESeq. My desire…
Answer: GWAS Phenotypes
by
韩雨
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In my opinion, the basis of the question is to solve whether the phenotype is regulated by genetics. In the aspect of genetic, the estima…
Answer: Classic threshold for log2 fold change in RNA-seq experiment
by
May Ling
• 0
Good day everyone, Sorry I found a bit confusing and would appreciate if I could clarify on the calculation. I am using DESeq. My desire…
Comment: some error in building kraken2 database
by
ahmet
• 0
Were you able to fix this issue? I'm also trying to add external species to krakendb
Comment: Z score
by
ATpoint
82k
logFCs are a bit difficult to cluster I think, because fold changes without stats attached to it are meaningless. They can be very big, due…
Comment: Z score
by
Akash D
▴ 40
Ok. However, if i perform it on log2FC, there wont be any control samples visible in my heatmap. Your answer is perfect.
Comment: Z score
by
ATpoint
82k
You can apply Z-scores on whatever you want, but it must make sense and depends on what you want to do. What is the context? See for exampl…
Answer: Z score in RNAseq
by
Akash D
▴ 40
Can Z score be applied on log2FC and then visualized? Alternatively, Can log2FC be converted to Z scores and then visualized as heatmap?
Comment: Ideal PC configurations and operating system for bioinformatics laboratory
by
ATpoint
82k
Just for comparison, I deal with scRNA-seq daily and my workstation is a 12700k i7 with 128GB RAM and even this is actually more than I nee…
Answer: Ideal PC configurations and operating system for bioinformatics laboratory
by
colindaven
6.4k
- As others have said, 1-2 workstations are probably the way to go. - A Linux OS like Ubuntu is probably easiest and has best docs - RA…
Comment: How to get the ratio of allele counts from GATK derived VCF file?
by
anikcropscience
▴ 230
Ok, thank you for the reply. I will check out the DP field then.
Comment: Alternatives To Liftover
by
Thanujay S
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Hey! Would you consider building an API for the same? Is that something you have planned?
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